Overview
Reactive arthritis is joint pain and swelling triggered by an infection in another part of the body — most often the intestines, genitals or urinary tract.
This condition usually targets the knees, ankles and feet. Inflammation also can affect the eyes, skin and the tube that carries urine out of the body (urethra). Previously, reactive arthritis was sometimes called Reiter’s syndrome.
Reactive arthritis isn’t common. For most people, signs and symptoms come and go, eventually disappearing within 12 months.
Symptoms
The signs and symptoms of reactive arthritis generally start 1 to 4 weeks after exposure to a triggering infection. They might include:
- Pain and stiffness. The joint pain associated with reactive arthritis most commonly occurs in the knees, ankles and feet. Pain may also occur in the heels, low back or buttocks.
- Eye inflammation. Many people who have reactive arthritis also develop eye inflammation (conjunctivitis).
- Urinary problems. Increased frequency and discomfort during urination may occur, as can inflammation of the prostate gland or cervix.
- Inflammation of tendons and ligaments where they attach to bone (enthesitis). This happens most often in the heels and the sole of the feet.
- Swollen toes or fingers. In some cases, toes or fingers might become so swollen that they look like sausages.
- Skin problems. Reactive arthritis can affect skin in a variety of ways, including mouth sores and a rash on the soles of the feet and palms of the hands.
- Low back pain. The pain tends to be worse at night or in the morning.

Inflammation sites
Inflammation often affects these sites in people with reactive arthritis.
When to see a doctor
If you develop joint pain within a month of having diarrhea or a genital infection, contact your health care provider.