Numbness describes a loss of feeling in a part of the body. It also is often used to describe other changes in sensation, such as burning or a pins-and-needles feeling. Numbness can occur along a single nerve on one side of the body. Or numbness may occur on both sides of the body. Weakness, which is usually caused by other conditions, is often mistaken for numbness.

Causes

Numbness is caused by damage, irritation or compression of nerves. A single nerve branch or several nerves may be affected. Examples include a slipped disk in the back or carpal tunnel syndrome in the wrist. Certain diseases such as diabetes or toxins such as chemotherapy or alcohol can damage the longer, more-sensitive nerve fibers. These include the nerve fibers that go to the feet. The damage can cause numbness.

Numbness commonly affects nerves outside of the brain and spinal cord. When these nerves are affected, it can cause a lack of feeling in the arms, legs, hands and feet.

Numbness alone, or numbness associated with pain or other unpleasant sensations, isn’t usually due to life-threatening disorders such as strokes or tumors.

Your doctor needs detailed information about your symptoms to diagnose the cause of your numbness. A variety of tests may be needed to confirm the cause before treatment can begin.

Possible causes of numbness include:

Brain and nervous system conditions
Acoustic neuroma
Brain aneurysm
Brain AVM (arteriovenous malformation)
Brain tumor
Guillain-Barre syndrome
Herniated disk
Paraneoplastic syndromes of the nervous system
Peripheral nerve injuries
Peripheral neuropathy
Spinal cord injury
Spinal cord tumor
Stroke
Transient ischemic attack (TIA)
Transverse myelitis
Trauma or overuse injuries
Brachial plexus injury
Carpal tunnel syndrome
Frostbite
Chronic conditions
Alcohol use disorder
Amyloidosis
Charcot-Marie-Tooth disease
Diabetes
Fabry’s disease
Multiple sclerosis
Porphyria
Raynaud’s disease
Sjogren’s syndrome
Infectious diseases
Leprosy
Lyme disease
Shingles
Syphilis
Treatment side effects
Side effects of chemotherapy or anti-HIV drugs
Other causes
Heavy metal exposure
Thoracic aortic aneurysm
Vasculitis
Vitamin B-12 deficiency

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